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Correlation analysis among proteins and with laboratory characteristics. Significant correlations among proteins, with the strongest correlation between interleukin (IL)‐6 and IL‐10. (A) Correlation between vascular endothelial growth factor (VEGF) and <t>granulocyte</t> <t>colony‐stimulating</t> factor (GCSF) levels. (B) Correlation between IL‐10 and angiopoietin‐2 levels. (C) Correlation between IL‐6 and angiopoietin‐2 levels. (D) Correlation between VEGF and angiopoietin‐2 levels. (E) Correlation between IL‐10 and IL‐6 levels. (F) Correlation between IL‐10 and LDH levels. (G) Correlation between angiopoietin‐2 levels and reticulocyte counts. A best‐fit linear regression line with 95% confidence bands (dotted line) is shown. Spearman's correlation coefficient ( ρ ) and p values ( P ) are given, with p < 0.05 being statistically significant.
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Correlation analysis among proteins and with laboratory characteristics. Significant correlations among proteins, with the strongest correlation between interleukin (IL)‐6 and IL‐10. (A) Correlation between vascular endothelial growth factor (VEGF) and <t>granulocyte</t> <t>colony‐stimulating</t> factor (GCSF) levels. (B) Correlation between IL‐10 and angiopoietin‐2 levels. (C) Correlation between IL‐6 and angiopoietin‐2 levels. (D) Correlation between VEGF and angiopoietin‐2 levels. (E) Correlation between IL‐10 and IL‐6 levels. (F) Correlation between IL‐10 and LDH levels. (G) Correlation between angiopoietin‐2 levels and reticulocyte counts. A best‐fit linear regression line with 95% confidence bands (dotted line) is shown. Spearman's correlation coefficient ( ρ ) and p values ( P ) are given, with p < 0.05 being statistically significant.
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Correlation analysis among proteins and with laboratory characteristics. Significant correlations among proteins, with the strongest correlation between interleukin (IL)‐6 and IL‐10. (A) Correlation between vascular endothelial growth factor (VEGF) and <t>granulocyte</t> <t>colony‐stimulating</t> factor (GCSF) levels. (B) Correlation between IL‐10 and angiopoietin‐2 levels. (C) Correlation between IL‐6 and angiopoietin‐2 levels. (D) Correlation between VEGF and angiopoietin‐2 levels. (E) Correlation between IL‐10 and IL‐6 levels. (F) Correlation between IL‐10 and LDH levels. (G) Correlation between angiopoietin‐2 levels and reticulocyte counts. A best‐fit linear regression line with 95% confidence bands (dotted line) is shown. Spearman's correlation coefficient ( ρ ) and p values ( P ) are given, with p < 0.05 being statistically significant.
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Correlation analysis among proteins and with laboratory characteristics. Significant correlations among proteins, with the strongest correlation between interleukin (IL)‐6 and IL‐10. (A) Correlation between vascular endothelial growth factor (VEGF) and <t>granulocyte</t> <t>colony‐stimulating</t> factor (GCSF) levels. (B) Correlation between IL‐10 and angiopoietin‐2 levels. (C) Correlation between IL‐6 and angiopoietin‐2 levels. (D) Correlation between VEGF and angiopoietin‐2 levels. (E) Correlation between IL‐10 and IL‐6 levels. (F) Correlation between IL‐10 and LDH levels. (G) Correlation between angiopoietin‐2 levels and reticulocyte counts. A best‐fit linear regression line with 95% confidence bands (dotted line) is shown. Spearman's correlation coefficient ( ρ ) and p values ( P ) are given, with p < 0.05 being statistically significant.
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Correlation analysis among proteins and with laboratory characteristics. Significant correlations among proteins, with the strongest correlation between interleukin (IL)‐6 and IL‐10. (A) Correlation between vascular endothelial growth factor (VEGF) and <t>granulocyte</t> <t>colony‐stimulating</t> factor (GCSF) levels. (B) Correlation between IL‐10 and angiopoietin‐2 levels. (C) Correlation between IL‐6 and angiopoietin‐2 levels. (D) Correlation between VEGF and angiopoietin‐2 levels. (E) Correlation between IL‐10 and IL‐6 levels. (F) Correlation between IL‐10 and LDH levels. (G) Correlation between angiopoietin‐2 levels and reticulocyte counts. A best‐fit linear regression line with 95% confidence bands (dotted line) is shown. Spearman's correlation coefficient ( ρ ) and p values ( P ) are given, with p < 0.05 being statistically significant.
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Correlation analysis among proteins and with laboratory characteristics. Significant correlations among proteins, with the strongest correlation between interleukin (IL)‐6 and IL‐10. (A) Correlation between vascular endothelial growth factor (VEGF) and <t>granulocyte</t> <t>colony‐stimulating</t> factor (GCSF) levels. (B) Correlation between IL‐10 and angiopoietin‐2 levels. (C) Correlation between IL‐6 and angiopoietin‐2 levels. (D) Correlation between VEGF and angiopoietin‐2 levels. (E) Correlation between IL‐10 and IL‐6 levels. (F) Correlation between IL‐10 and LDH levels. (G) Correlation between angiopoietin‐2 levels and reticulocyte counts. A best‐fit linear regression line with 95% confidence bands (dotted line) is shown. Spearman's correlation coefficient ( ρ ) and p values ( P ) are given, with p < 0.05 being statistically significant.
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Correlation analysis among proteins and with laboratory characteristics. Significant correlations among proteins, with the strongest correlation between interleukin (IL)‐6 and IL‐10. (A) Correlation between vascular endothelial growth factor (VEGF) and granulocyte colony‐stimulating factor (GCSF) levels. (B) Correlation between IL‐10 and angiopoietin‐2 levels. (C) Correlation between IL‐6 and angiopoietin‐2 levels. (D) Correlation between VEGF and angiopoietin‐2 levels. (E) Correlation between IL‐10 and IL‐6 levels. (F) Correlation between IL‐10 and LDH levels. (G) Correlation between angiopoietin‐2 levels and reticulocyte counts. A best‐fit linear regression line with 95% confidence bands (dotted line) is shown. Spearman's correlation coefficient ( ρ ) and p values ( P ) are given, with p < 0.05 being statistically significant.

Journal: British Journal of Haematology

Article Title: Circulating angiogenesis‐related biomarkers in sickle cell retinopathy and maculopathy

doi: 10.1111/bjh.70385

Figure Lengend Snippet: Correlation analysis among proteins and with laboratory characteristics. Significant correlations among proteins, with the strongest correlation between interleukin (IL)‐6 and IL‐10. (A) Correlation between vascular endothelial growth factor (VEGF) and granulocyte colony‐stimulating factor (GCSF) levels. (B) Correlation between IL‐10 and angiopoietin‐2 levels. (C) Correlation between IL‐6 and angiopoietin‐2 levels. (D) Correlation between VEGF and angiopoietin‐2 levels. (E) Correlation between IL‐10 and IL‐6 levels. (F) Correlation between IL‐10 and LDH levels. (G) Correlation between angiopoietin‐2 levels and reticulocyte counts. A best‐fit linear regression line with 95% confidence bands (dotted line) is shown. Spearman's correlation coefficient ( ρ ) and p values ( P ) are given, with p < 0.05 being statistically significant.

Article Snippet: In addition, the following ELISA‐kits were used: Ang‐2 (ELH‐Angiopoietin2‐1), granulocyte colony‐stimulating factor (GCSF; ELH‐GCSF‐1), endoglin (ELH‐Endoglin‐1), endostatin (ELH‐ENDOSTATIN‐1), IL‐6 (ELH‐IL6‐1) and IL‐10 (ELH‐IL10‐1), all from RayBiotech (Norcross GA, USA).

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